Kinetics of Cryptosporidium parvum sporozoite neutralization by monoclonal antibodies, immune bovine serum, and immune bovine colostrum
نویسندگان
چکیده
منابع مشابه
Protection of calves against cryptosporidiosis with immune bovine colostrum induced by a Cryptosporidium parvum recombinant protein.
The purpose of the study was to determine if immunization with a recombinant protein (rC7) of Cryptosporidium parvum would induce immune bovine colostrum that protected calves against cryptosporidiosis following oral challenge with C. parvum oocysts. Late gestation Holstein cows with low titers of antibody to the p23 antigen of C. parvum were immunized three times with 300 microg affinity purif...
متن کاملImmune components of bovine colostrum and milk.
Colostrum and milk provide a complete diet for the neonate. In ruminants, colostrum is also the sole source of initial acquired immunity for the offspring. Milk therefore plays an important role in mammalian host defense. In colostrum, the concentration of immunoglobulins is particularly high, with IgG being the major immunoglobulin class present in ruminant milk, in contrast to IgA being the m...
متن کاملThe Immune Proteins of Bovine Colostrum
The important r61e of the colostrum in the transmission of antibodies from mother to offspring, and particularly in the protection of the new-born in ruminants to infectious disease, has been shown by the work of many investigators (1). Howe has demonstrated by salt fractionation studies that the serum of t)he new-born calf taken prior to suckling is deficient in a globulin fraction, and that t...
متن کاملThe immune proteins of bovine colostrum and plasma.
The important r61e of the colostrum in the transmission of antibodies from mother to offspring, and particularly in the protection of the new-born in ruminants to infectious disease, has been shown by the work of many investigators (1). Howe has demonstrated by salt fractionation studies that the serum of t)he new-born calf taken prior to suckling is deficient in a globulin fraction, and that t...
متن کاملDetection of Cryptosporidium parvum oocysts in bovine feces by monoclonal antibody capture enzyme-linked immunosorbent assay.
A monoclonal antibody enzyme-linked immunosorbent assay (ELISA) was developed to detect Cryptosporidium parvum oocysts in bovine feces. Fecal oocysts were concentrated by centrifugation through Formalin-ethyl acetate solution and captured with monoclonal antibody 18.280.2 reactive with C. parvum oocysts. Captured oocysts were detected with goat anti-oocyst serum, following the addition of a per...
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ژورنال
عنوان ژورنال: Infection and Immunity
سال: 1990
ISSN: 0019-9567,1098-5522
DOI: 10.1128/iai.58.1.257-259.1990